Periodontal disease has been hypothesized to have an effect on many different systemic diseases. This site presents some of the research that suggests links to the more common diseases. Different pathways have been suggested to link periodontal diseases to various systemic diseases. Periodontitis activates the immune and inflammatory system, which results in a systemic inflammation. The systemic inflammation might be the plausible explanation of the association between periodontitis and other conditions. We do know that periodontal disease contributes to systemic inflammation and that this has a negative effect on the overall body. Periodontal disease and other systemic conditions share many risk factors such as smoking, diabetes and increasing age. Periodontitis, like many of the systemic diseases, is multifactorial which makes it complex when discussing aetiology, progression and evidence.
Bui et al. 2019, Hedge and Awan 2019, Sabharwal et al. 2018, Herrera et al. 2018, Holmstrup et al. 2017, Igari et al. 2014