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Chronic Kidney Diseases and Periodontal Disease

Chronic kidney disease is a loss of kidney function, with the end therapy being dialysis or a transplant. Systemic inflammation, increasing age, smoking, hypertension and uncontrolled diabetes are some of the risk factors for chronic kidney diseases.

Some evidence suggests a possible association between periodontitis and chronic kidney disease but evidence for a bidirectional link is weak. The mechanisms connecting these two diseases are not fully known, but it is suggested the chronic low-grade systemic inflammation from periodontitis and/or the oral bacteria triggers an inflammatory response and progression of the kidney disease.

 

Periodontal treatment and good oral hygiene are a benefit for all patients since it reduces the preventable burden of the systemic inflammation associated with periodontal disease.

 

Kapellas et al. 2019, Chambrone et al. 2013

https://prod.tepe.com/contentassets/a1d52ca1664a41d0ab82ccb7ca42caa5/wd192332int_kidney_1200x630.jpg